The results of his research activity have been published in over 700 scientific works, including: the author of Atherosclerosis of arteries monograph (1967) and co-author of other nine monographs: Atherosclerosis and elasticity of arteries (1970), Enzymes of arteries and atherosclerosis (1973), Morphogenesis of atherosclerosis (1982), Ultrastructural bases of atherosclerosis of arteries (1983), Damaged cardiomyocyte (1991), Incipient atherosclerosis (1991), Atherogenesis and immune inflammation (1997), Atherogenesis (aspects of pathobiology) (2001), Atherosclerosis and Diabetes (2006);
Author of several textbooks and methodological recommendations;
Trained over 100 Doctors and Habilitated Doctors in Medical Sciences;
Developed the theory of incipient atherosclerosis, introducing new notions in the genesis of this phenomenon;
The detection of early phases of atherogenesis constitutes a fundamental, original discovery, a future research direction;
He founded the Scientific School of Morphopathologists in the republic;
As rapporteur, coordinator, member of the organizing committees, chairman, co-chairman, he represented the Republic of Moldova at European and world scientific forums (congresses, conferences and symposia) in Moscow, St. Petersburg, Tokyo, Kiev, Valencia (Spain), Washington, Helsingor (Denmark), Nice (France), Berlin, Rome, Bucharest, Prague, Paris, Istanbul, Lisbon, Montreal etc.